Solution stability of Captisol-stabilized melphalan (Evomela) versus Propylene glycol-based melphalan hydrochloride injection
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چکیده
منابع مشابه
Stability of melphalan solution for intravitreal injection for retinoblastoma.
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Melphalan is an alkylating agent frequently used in an intravenous formulation to treat hematologic malignancies and solid tumors in both adults and children. According to the manufacturer, melphalan is stable in sterile 0.9% sodium chloride for 90 min at room temperature (RT). Several authors have studied the stability of different concentrations of melphalan; however, most were not adapted to...
متن کاملpropylene glycol , and ethylene glycol - based antifreeze
of AF performance. that contain EG has been reponed to result in irreversible damage to renal, hepatic, cardiovascular, and central nervous systems, and is a cause of death in household pets and other animals.2-4 It is not known why some animals ingest EGcontaining products. Although there are reports suggesting that the "sweet" taste of EG, and of products containing it, may lead to ingestion ...
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ژورنال
عنوان ژورنال: Pharmaceutical Development and Technology
سال: 2016
ISSN: 1083-7450,1097-9867
DOI: 10.1080/10837450.2016.1265557